Top 5 Cancer Stories of 2015

2015 has been a landmark year in cancer research. There were many groundbreaking news and stories worth talking in 2016. Here are some of the most interesting stories.

#5- Immunotherapy Hope for Colorectal Cancer Subtype

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Mung T.Le, M.D. presented how DNA of a cancer tumor can mutate, affecting their DNA repair machinery. Patients with mismatch repair (MMR) deficiency may respond differently to certain immunotherapies. This study is considered a major breakthrough because it looked at how tumor’s genetics could guide immunotherapy.

#4- FDA Approval for Kidney Cancer Immunotherapy


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FDA approved checkpoint inhibitors for kidney cancer in 2015. Opdivo was the first FDA approval of this type. It works on the PD-1 checkpoint and it can be used to treat metastatic kidney cancer. Opdivo has shown to help overall survival and causes less serious side effects compared to other checkpoint inhibitors.

#3- Immunotherapy Combinations Show Promise in Melanoma


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This year’s ASCO was a success as there were numerous immunotherapy news. Dr. Jedd presented important data on melanoma, revealing combination of different inhibitors, particularly Yervoy and Opdivo. The combination of these two have impact on progression-free survival, extending the average to 11.5 months.

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